Thursday 12 December 2013

Erdheim-Chester Disease

Erdheim–Chester disease

It is also known as polyostotic sclerosing histiocytosisor Erdheim–Chester syndrome. It is a infrequentillnessconsidered by the irregularincrease of a precise type of white blood cells called histiocytes, or tissue macrophages (technically, this illness is called a non-Langerhans-cell histiocytosis). Typically, onset is in middle age.


Symptoms
Erdheim-Chester can include many dissimilarschemes in the body and most often touches the long bones. In order of incidence, it also happens in the kidney, retroperitoneum, brain, skin,lung, and tissue behind hand the pituitary gland,eyes, and heart

Diagnosis
Histologyand Radiologic osteosclerosisare the main analytic features.

Treatment

High-dose Corticosteroid therapy, Surgical debulking, Cyclosporin, Interferon,Chemotherapy.








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