Tuesday, 11 February 2014

Machado-Joseph Disease

Machado-Joseph Disease  

It is a very uncommon autosomal dominant neurodegenerative disease. It causes slow cerebellar ataxia which leads to lack of muscular control and coordination of the upper and lower parts. 


 
SYMPTOMS:    
Symptoms are memory defects, dificuties in speech, dysphagia, spasticity, muscular weakness, involuntary urination and eye movement, clumsiness and may even lead to paralysis.


DIAGNOSIS:
It is diagnosed by clinical features. Genetic studies are also conducted.


TREATMENT:

There are no specific treatments. Treatments are symptomatic. Levodopa and beclofan can be used. Physiotherapy can also be conducted.








1 comment:

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