Wiskott
- Aldrich syndrome
Wiskott -
Aldrich syndrome is a rare and inherited immune deficiency disorder and a
reduced ability to form blood clot. It primary affects males because WAS is an
X-linked recessive genetic condition. Patients are highly susceptible to
bacterial and fungal infection and eczema. Children with WAS are usually
diagnosed in 1-2years after birth.
Symptoms – Though the symptoms vary among patients, the
common one includes easy bruising & bleeding, nose bleeds, intestinal &
intracranial bleeding, herpes simplex, bacterial or vital pneumonia.
Treatment
– The
only proven cure for WAS is bone marrow or cord blood transplant, other
treatment includes antibacterial, antifungal and antiviral medications,
intravenous immunoglobulin infusions, platelet transfusion and to minimize
exposure to infections and risk of head trauma.
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