Lennox-Gastaut Syndrome

Lennox-Gastaut Syndrome

It is early-onset epilepsy that is common between 2^nd to 6^th decades of life. 

SYMPTOMS:

I is characterized by multiple seizures. It shows similarity with west syndrome. It also shows psychological, behavioral and developmental disorders.  

DIAGNOSIS:

The diagnosis is based on the occurrence of seizures and the spike wave pattern on the EEG.

TREATMENT:

1.      Pharmacological:

              a. Approved line of drugs

             b. First line of drugs: rufinamide

              c.. Second line of drugs: felbamate

             d. Unapproved line of drugs: vigabatrin

2.      Surgical

a. Vagus nerve stimulation

b. Corpus callosotomy

3.      Others

a. Ketogenic diet

b. Intravenous immunoglobin therapy